Writing
I’ve written for more than three decades about medicine, biology, technology, innovation, and health. This page collects a few favorites, recurring themes, and longer archives.
Favorites
Pieces I especially like, and that together give a reasonable sense of the things I’ve been thinking about over the years.
- The Bedside Profession
- Back to the Future: Medicine and Our Genes
- The Molecular Biography of the Cell
- Balancing Disruptive Innovation and Incremental Progress in Medicine
- What Silicon Valley Doesn’t Understand About Medicine
- Learning From History How to Think About the Technology of the Moment
- Success in Film and Pharma: Contingent but Not Random
- Nobody Ever Got Younger, but It May Be Worth a Try
- The Narrative Machine: What AI Really Adds to Personal Health Data
- Agency: The Motivational Currency of Health
- When AI Tells a Story About Your Health, Is It True?
By theme
Foundations: Medicine, Biology + the Individual
Genetics + Precision Medicine
- Can We Pick Winners With Causal Human Biology? Vertex Makes the Case
- Precision Medicine: Seeking Impact, Needing Champions
- Next Hurdle for Medical Research: Capture and Integration of Phenotype at Scale
- Turning Information Into Impact: Digital Health’s Long Road Ahead
- Back to the Future: Medicine and Our Genes
Technology, Innovation + R&D
- Artificial Intelligence in Drug Discovery—What It Is, Where We Stand and the Path Forward
- Learning From History How to Think About the Technology of the Moment
- A Drug Is Not an Outcome: Extending Translation Through Implementation Using Real-World Data
- The Startling History Behind Merck’s New Cancer Blockbuster
- What Silicon Valley Doesn’t Understand About Medicine
Measurement, Models + Meaning
- When AI Tells a Story About Your Health, Is It True?
- The Narrative Machine: What AI Really Adds to Personal Health Data
- Context-Aware Monitoring: Rethinking Comprehensive Screening in the Era of AI
- Quantified Self Redux?
- We Are Not a Dashboard
- Captivating Moonrise Podcast Series Highlights Role of Narrative in Technology Adoption